
Research Interests
My research interests lie in the area of
neural coding in sensory systems. Using the gustatory system as a model,
my graduate students and I have pursued two separate but interrelated strategies.
First, we have presented the system with an array of natural stimuli, i.e.
examples of various taste qualities, and recorded the electrophysiological
responses from taste-sensitive neurons in anesthetized rats. By the analysis
of the spike trains evoked in small groups of simultaneously recorded neurons,
we have been able to deduce some of the interrelationships among taste cells
that produce their characteristic sensitivity patterns. As part of this
effort, we have proposed a neural network model of taste processing in the
brain stem. Although it is still evolving, our model demonstrates the possibility
that some of the well studied features of taste-responsive neurons may actually
be emergent properties of network processing, rather than intrinsic characteristics.
As a second, complimentary strategy we have driven taste-related neurons
with electrical pulses presented in a temporal sequence that mimics the
temporal pattern of the neural response to a natural tastant. We then assess
the evoked sensation in terms of its similarity to a natural taste. By systematically
varying the temporal parameters of this artificial stimulus, i.e. the electrical
stimulation, we hope to discover which aspects of the neural response evokes
the various characteristics of a taste perception.
Contact Information
Contact Patricia M. Di Lorenzo, S4, 128
or G72.
Types of Research Experiences Available
Depending on the qualifications of the
student, undergraduate research assistants may be involved in all aspects
of experimental design, data collection analysis, and write-up. Both behavioral
and electrophysiological experiments are ongoing at all times in the laboratory.
Particularly well-qualified students may design their own projects. Weekly
lab meetings include discussion of assigned readings from the scientific
literature.
Specific Prerequisites
Introduction to Psychology, Physiological
Psychology, a keen sense of responsibility and motivation and a good sense
of humor.
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If you have questions or comments, please e-mail us at psybio@binghamton.edu.
This page was last updated on 7/14/00. |
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